KINCEF-S 1.5g (CEFTRIAXONE 1g + SULBACTAM 0.5g for Injection) I.M/I.V.
Generic Name: Ceftriaxone and Sulbactam
Brand Name: Kincef-S.
Class: Third-generation cephalosporins with beta-lactamase inhibitor.
Strength: 1.5 g (per vial).
Form: Powder for injection (reconstituted with sterile water for injections).
Amount: ₦‎2,000.

Description: Kincef-S. is an antibiotic combination used to treat infections caused by Ceftriaxone-sensitive pathogens. It is effective in conditions such as sepsis, meningitis, abdominal infections (e.g., peritonitis, biliary tract infections), bone and joint infections, soft tissue infections, skin wounds, respiratory tract infections (including pneumonia), and uncomplicated gonorrhoea. It can also be used for peri-operative prophylaxis to reduce postoperative infection risk.

Key Features:
• Combines Ceftriaxone’s broad-spectrum antibacterial action with Sulbactam’s beta-lactamase inhibition.

Side Effects:
• Common side effects include diarrhoea, localized reactions at the injection site, and skin itching. Serious side effects are rare but may include severe stomach pain, bloody diarrhoea (even months after use), and signs of infection. Dosage adjustments are needed for patients with renal impairment.

Cautions:
• Allergic reactions to cephalosporin antibiotics should be considered.
• Adjust dosage in patients with renal impairment based on creatinine clearance.
• Follow prescribed doses carefully, especially in paediatric patients.