COAXIN (Dihydroartemisinin/piperaquine 40mg/320mg) x 9 TABLETS.

COAXIN (Dihydroartemisinin/piperaquine 40mg/320mg) x 9 TABLETS.
Generic Name: Dihydroartemisinin/piperaquine.
Brand Name: Coaxin.
Class: Antimalarial
Pack Size: 9 tablets.
Strength: Each tablet contains 40 mg dihydroartemisinin and 320 mg piperaquine (as phosphate).
Amount: ₦2,000.

Description: Coaxin is a fixed-dose combination antimalarial medication used for the treatment of uncomplicated malaria caused by Plasmodium falciparum or Plasmodium vivax.

Key Features:
• Effective against all Plasmodium species that cause malaria in humans.
• Taken as a 3-day course, with one tablet taken once daily.
• Dosing based on body weight, ranging from 1 to 5 tablets per day.
• Can be taken with or without food.
• Tablets can be crushed and mixed with water if needed.

Side Effects:
• Uncommon side effects include cardiac disorders (QT prolongation, tachycardia), gastrointestinal disturbances, pruritus, hepatic disorders, and joint/muscle pain.
• Patients should be monitored for cardiac effects, especially when combined with other drugs that prolong the QT interval.

Cautions:
• Do not use in patients with cardiac disorders (bradycardia, heart rhythm disorders, congestive heart failure).
• Do not combine with drugs that prolong the QT interval (e.g. amiodarone, other antimalarials, antipsychotics).
• Use with caution in patients over 60 years old or with renal/hepatic impairment.